Designing successful clinical trials requires balancing a complex set of tradeoffs, including statistical power, sample size, recruitment timelines, operational feasibility, study cost, site selection, and the ability to generate meaningful clinical learnings. Suboptimal design choices can lead to delays, underpowered studies, excessive costs, or reduced probability of regulatory and clinical success. Cardinal Trials addresses this challenge by benchmarking proposed trial designs against similar historical studies sourced from ClinicalTrials.gov. The platform provides comparative visual analytics of key design parameters to help clinical teams assess feasibility, select sites, and optimize trial design decisions.